The Bundesliga side has already topped the group and qualified for the next round, while Roberto Mancini's team must win and hope that Real Madrid beats Ajax at home.
Borussia Dortmund attacker Marco Reus (pictured) has scored the first goal of the game in three of his last four Champions League appearances.
Dortmund has made more defensive clearances than any other team in the Champions League (248).
Manchester City has won one and lost four of its previous European trips to Germany.
Tip: Borussia, Odds: 2.20
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